IN THE NEWS
Three Labs are Better than One
Recent news reports have announced the surprising and promising effects of rapamycin (August Newsletter), the first pharmaceutical known to extend healthy life in mice. Dr. Z. David Sharp's idea to test this drug on mice was simply a wish until he connected with ITP. ITP is the Interventions Testing Program of the National Institute on Aging (NIA). This Program took Dave's ideas from concept to reality with efficiency and credibility.
The Interventions Testing Program is only 5 years old but already it has proven to provide a practical solution. According to Huber Warner, the founder of the program, “It occurred to me that I saw lots of papers from grantees of the NIA about slowing down aging and expending lifespan but they were rarely backed up and given credibility through testing.” Huber realized that a focused program was needed so that more than one lab was confirming whether an intervention works. He proposed the idea to the NIA that led to the Intervention Testing Program.
ITP generally selects studies based on treatments that are easily obtainable, reasonably priced and delivered in the food of the mice. The research is conducted in three labs, chosen by ITP, to conduct the tests with mice: University of Michigan, Jackson Laboratories in Maine and University of Texas Health Sciences Center at San Antonio. Three labs working simultaneously accelerate the testing process. Dave Sharp also notes, “The three labs have no intellectual stake in the results. This is scientifically significant and further validates the success.”
Mprize competitor Bruce Teter (see related article) is working with ITP now to test curcumin. Tests have been conducted with aspirin, green tea extract and other interventions. The results with rapamycin are the first major breakthrough from an ITP study, with strong results in rejuvenation and extended lifespan in both male and female mice. 
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Featured Testimonial
The newest members of the 300 have this to share:
“It seems a cruel joke that just when we've finally lived long enough to become wise, we begin the great decline into physical and mental deterioration that eventually leads to death.”
The Royal-Gordon Family
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Scientific Advisory Board Member
Christiaan Leeuwenburgh Phd
“I am enthusiastic about all that is happening in research related to longevity and rejuvenation. There are several areas I am interested in pursuing further, all related to maintaining strong, healthy minds and bodies.”
Recognizing The
Last Call! Many thanks to our special group of donors, the 300. Responding to the Methuselah Foundation challenge to contribute $85 a month for 25 years, this farsighted group has made the progress you read about in this newsletter possible.
There are a few remaining slots left, join now and your donation will go to work immediately funding innovative technology that will change science forever.
As a 300 member you will receive advance notice of news and events, have the opportunity to participate in exclusive webinars, receive a monthly email from Dave Gobel and have the satisfaction of knowing your gift will result in extended healthy life for yourself, your family and all humanity.
More news on The 300 monument coming soon - join now and have your name and message included.
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Follow the Mice
Recent changes to our website include updates on our Mprize Competitors. Follow the progress of the mice and get updates from the researchers on their latest work. ___________________________________________________________________
A Unique Take on PSAs
Methuselah Foundation has created four Public Service Announcements. You'll see these unique, fun and decidedly different PSAs on web distribution channels Hulu and Vimeo. This image is from a 15 second spot, take a look and tell us what you think.
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