Methuselah's Zoo
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Scientists are searching for ways to extend the healthy human lifespan, but an Alabama researcher thinks they’re studying the wrong animals in their quest for longer life.
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New Research Suggests Anti-Malarial Drug may Extend Lifespan
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Scientists have long suspected that the anti-malarial drug chloroquine may be helpful in treating senescence, the gradual, age-related deterioration of function in living organisms. The problem is that research has found the drug comes with some nasty side-effects, including liver damage, an increased risk of cardiac arrythmia, and gastrointestinal issues.
Read MoreVascular Tissue Challenge Update
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Last June, the Methuselah Foundation and NASA officially launched the Vascular Tissue Challenge (VTC) at the White House Organ Summit, hosted by the Office of Science and Technology Policy. The VTC includes a $500,000 prize purse from NASA for the first teams that can successfully create thick (>1cm), vascularized tissues that remain functional and alive for more than 30 days. Along with this is the Center for the Advancement of Science in Space’s (CASIS) “Innovations in Space Award,” providing an additional $200,000 to support a research opportunity onboard the International Space Station’s National Laboratory!
Read MoreOrganovo Collaborates With Professor Melissa Little for Kidney Tissue Research
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SAN DIEGO and MELBOURNE, Australia and SPRINGFIELD, Va., Jan. 24, 2017 (GLOBE NEWSWIRE) -- Organovo Holdings, Inc. (NASDAQ:ONVO) (“Organovo”), a three-dimensional biology company focused on delivering scientific and medical breakthroughs using its 3D bioprinting technology, today announced a collaboration with Professor Melissa Little and the Murdoch Childrens Research Institute, The Royal Children’s Hospital, Melbourne, Australia to develop an architecturally correct kidney for potential therapeutic applications. The collaboration has been made possible by a generous gift from the Methuselah Foundation (“Methuselah”) as part of its ongoing University 3D Bioprinter Program.
Read MoreScientists Correct Mutated Gene that Causes Sickle Cell Disease in Stem Cells
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For the first time, scientists were able to correct the genetic mutation that causes sickle cell disease in stem cells.
In a collaborative effort, researchers at UC Berkeley, UC San Francisco Benioff Children’s Hospital Oakland Research Institute (CHORI), and the University of Utah School of Medicine fixed the mutation in modified stem cells from patients with the condition using a CRISPR/Cas9 gene editing approach.
Read MoreThese companies search for a cure to aging– and their discoveries are amazing
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The ideas surrounding life enhancement are not new—in fact, records show an interest in the mysteries surrounding human life for centuries.
Mary Shelley’s Frankenstein explores the idea of creating a life, while Doctor Who achieves life extension through regeneration. Wolverine's mutations let him heal away his problems, and Captain America froze himself into the 21st century. Just look at almost any Star Trek episode and you’ll see how fascinated people are with the idea of extending life.
Read MoreIrish scientists discover way to 'print' new bones to help those with deformities and catastrophic injuries
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Irish scientists have developed a revolutionary new process which allows them to make human bones using 3D printing.
The new process could eliminate the need for bone grafts and could even make new joints to replace hips and knees and offers hope to those with large and complex bone defects or who have suffered catastrophic injuries.
Read MoreMaking memories stronger and more precise during aging
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When it comes to the billions of neurons in your brain, what you see at birth is what get — except in the hippocampus. Buried deep underneath the folds of the cerebral cortex, neural stem cells in thehippocampus continue to generate new neurons, inciting a struggle between new and old as the new attempts to gain a foothold in the memory-forming center of the brain.
In a study published online today in Neuron, Harvard Stem Cell Institute (HSCI) researchers atMassachusetts General Hospital and the Broad Institute of MIT and Harvard in collaboration with an international team of scientists found they could bias the competition in favor of the newly generated neurons.
Read MoreVascular Tissue Challenge Introduction Webinar
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The Vascular Tissue Challenge is a $500,000 prize purse for the creation ofthick, human vascularized organ tissue in an in-vitro environment that maintains metabolic functionality similar to in vivo native cells throughout a 30-day trial period. The Methuselah Foundation's New Organ Alliance and NASA's Centennial Challenges Program have partnered to create this challenge with the goal of advancing research on human physiology, fundamental space biology, and medicine taking place both on the Earth and the ISS National Laboratory.
Read MoreEpisode 005 with Dr John Geibel; Yale University
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On this week's podcast, join us as we talk with Dr John Geibel, Director of Surgical Research and Professor of Department of Cellular and Molecular Physiology at Yale University. Discover how his team is working hard to develop the first iterations of 3-D printable organs, a goal that will revolutionize the medical organ industry and save thousands upon thousands of lives.
Read MoreMethuselah 300 Podcast Episode 004: Is a Synthetic Liver on the Horizon? With Dr Bryon Petersen
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Join us on this week's podcast as we interview Dr. Bryon Petersen, who is researching and developing a new device that could bridge the gap for those awaiting a new liver so that those in need can have a quality of life impossible for them now. You'll here about where he is in the stage of development, and what timeline he is working toward.
Read MoreEpisode 003 Interview with Founder Dave Gobel Part #2
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In this Episode of the Methuselah 300 Podcast, we’ll continue our interview with founder Dave Gobel as he explains more of the specific areas of regenerative medicine the foundation is working toward, some new partnerships and backers including NASA, and how he believes future life will be impacted in the near and mid term by exciting progress currently being made in medical research.
Read MoreEpisode 002 of the Methuselah 300 Podcast
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In this Episode of the Methuselah 300 Podcast, we’ll interview founder Dave Gobel and learn what planted the seed for the idea that would grow into the Methuselah Foundation. You’ll also learn the specifics of what innovations the foundation is working hard to create.
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