Researchers discover how cells repair structures that contribute to longevity
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A new study describes how cells repair damaged lysosomes, which promote longevity by eliminating or recycling cellular trash.
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Scientists leverage common virus for life extension
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Researchers at Rutgers New Jersey Medical School have found a way to use a common virus to deliver gene therapy that extended the lifespan of test mice, improved their physical performance, and reduced their cells’ age.
Read MoreBrown Fat Could Increase Lifespan and Healthful Aging
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One area of research for improving health and reducing the comorbidities of aging is brown adipose tissue. Brown adipose tissue improves energy metabolism and has protective mechanisms against obesity.
Read MoreVascular Tissue Challenge Update
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Last June, the Methuselah Foundation and NASA officially launched the Vascular Tissue Challenge (VTC) at the White House Organ Summit, hosted by the Office of Science and Technology Policy. The VTC includes a $500,000 prize purse from NASA for the first teams that can successfully create thick (>1cm), vascularized tissues that remain functional and alive for more than 30 days. Along with this is the Center for the Advancement of Science in Space’s (CASIS) “Innovations in Space Award,” providing an additional $200,000 to support a research opportunity onboard the International Space Station’s National Laboratory!
Read MoreScientists Correct Mutated Gene that Causes Sickle Cell Disease in Stem Cells
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For the first time, scientists were able to correct the genetic mutation that causes sickle cell disease in stem cells.
In a collaborative effort, researchers at UC Berkeley, UC San Francisco Benioff Children’s Hospital Oakland Research Institute (CHORI), and the University of Utah School of Medicine fixed the mutation in modified stem cells from patients with the condition using a CRISPR/Cas9 gene editing approach.
Read MoreThese companies search for a cure to aging– and their discoveries are amazing
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The ideas surrounding life enhancement are not new—in fact, records show an interest in the mysteries surrounding human life for centuries.
Mary Shelley’s Frankenstein explores the idea of creating a life, while Doctor Who achieves life extension through regeneration. Wolverine's mutations let him heal away his problems, and Captain America froze himself into the 21st century. Just look at almost any Star Trek episode and you’ll see how fascinated people are with the idea of extending life.
Read MoreMaking memories stronger and more precise during aging
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When it comes to the billions of neurons in your brain, what you see at birth is what get — except in the hippocampus. Buried deep underneath the folds of the cerebral cortex, neural stem cells in thehippocampus continue to generate new neurons, inciting a struggle between new and old as the new attempts to gain a foothold in the memory-forming center of the brain.
In a study published online today in Neuron, Harvard Stem Cell Institute (HSCI) researchers atMassachusetts General Hospital and the Broad Institute of MIT and Harvard in collaboration with an international team of scientists found they could bias the competition in favor of the newly generated neurons.
Read MoreNASA’s Vascular Tissue Challenge to help in study of deep space environmental effects
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Those working in the field of bioengineering should be ready for a challenge worth $500,000. NASA, along with the nonprofit Methuselah Foundation's New Organ Alliance, has introduced the new prize competition, named as the Vascular Tissue Challenge. The first three teams that will succeed in creating thick, metabolically-functional human vascularized organ tissue in a controlled laboratory environment will be offered the prize money.
Read MoreMethuselah 300 Podcast Episode 004: Is a Synthetic Liver on the Horizon? With Dr Bryon Petersen
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Join us on this week's podcast as we interview Dr. Bryon Petersen, who is researching and developing a new device that could bridge the gap for those awaiting a new liver so that those in need can have a quality of life impossible for them now. You'll here about where he is in the stage of development, and what timeline he is working toward.
Read MoreEpisode 003 Interview with Founder Dave Gobel Part #2
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In this Episode of the Methuselah 300 Podcast, we’ll continue our interview with founder Dave Gobel as he explains more of the specific areas of regenerative medicine the foundation is working toward, some new partnerships and backers including NASA, and how he believes future life will be impacted in the near and mid term by exciting progress currently being made in medical research.
Read MoreEpisode 002 of the Methuselah 300 Podcast
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In this Episode of the Methuselah 300 Podcast, we’ll interview founder Dave Gobel and learn what planted the seed for the idea that would grow into the Methuselah Foundation. You’ll also learn the specifics of what innovations the foundation is working hard to create.
Read MoreEpisode 001 of the Methuselah 300 Podcast
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In this episode, you'll learn what the podcast will be about and what you can expect to see in the future.
For more information and to see how you can help make a difference in the future of medicine, visit MFoundation.org
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