The latest on Methuselah, health span research, and regenerative medicine
Despite the vast population Alzheimer’s disease affects each year, no new drugs have been approved by the FDA in 16 years. The lack of success in AD drug development has infused scepticism in the field. This recent scientific publication shows the latest developments in the AD drug pipeline as of 2019.
Read MoreIn late 2018, a professor in Sweden conducted a study on the psychological and behavioral aspects of mobile phone use. Her study compiled data from 290 papers and lists some of her findings. Considering mental health is something essential for us to lead happy and healthy lives, and almost all of us use these devices daily, this paper is a good reminder for us all.
Read MoreBiomanufactured organs are the next frontier of scientific research and development. But creating vascularized tissue is a challenging endeavor, however a technique called SWIFT may get us one step closer to overcoming the hurdle of vascularization. They hope to continually improve upon this method with the goal of engineering fully functional, 3D printed human organs. Read what they learned below!
Read MoreIn a recent trial conducted in California, researchers investigated the effects that a recombinant human growth hormone had on the immune systems of 9 healthy men in their 50’s and 60’s. Over the course of one year, on average the trial members shed 2.5 years off of their ‘biological age’. It’s hoped that this newly acquired information regarding the effects these three drugs have on the body could be beneficial for people with under active immune systems, the elderly, and research into infectious diseases, cancer, and aging in general.
Read MoreWhen you hear the phrase, “Making 90 The New 50 By 2030”, does your mind go to the future? Thinking about the deadline? The work left to do? Or do you think about what’s already been accomplished? The progress already made? Because despite the work left to do, science has already come a long way towards reaching the goal. A study from 2018 conducted by Yale and USC Professors shows that in American males 60 might already be the new 50.
Read MoreIf you found a treatment that could to extend your life by up to 30% and increase your resistance to diseases and inflammation, what would you pay for it? What if it was free? That sounds like a no-brainer right? In 1980 one scientist stumbled upon such a treatment while conducting a study on high cholesterol, heart rate, and blood pressure involving rabbits.
Read MoreScientists have recently discovered a “master control gene” found in salamanders and worms called Early Growth Response that is also present in humans. What could this mean for us? This article explains some of the ins and outs of cell regeneration and how it might not be the presence of certain genes but rather, how they’re wired together that makes this level of cell regeneration possible.
Read MoreSince these “biomarkers” shorten as we age, many companies have begun to offer home tests to potentially show the users “true” biological age, how healthy they are, and their susceptibility to various diseases. But are these tests ready for the public? And is it worth your money to try one?
Read MoreIn the last 50 years the average life expectancy has been extended from 65 to 85, giving us an extra third of our life. Can we enjoy this substantial new chapter of life if we’re slowly being shackled by the bonds of aging? This article by the New Yorker discusses this intriguing topic!
Read MoreOne of our partners, Leucadia Therapeutics, is pleased to announce that Project Cribrose is now live! They are recruiting participants for a 2000 person study, including healthy people from 20-90 years old, those with Alzheimer’s disease, Frontotemporal dementia, or Down Syndrome and people over 50 with mild cognitive impairment.
Read MoreOn May 3 2019 Volumetric Bio made history, and made the cover of Science Magazine with their groundbreaking technology. But how does one go about photographing something smaller than a penny in sharp detail? This behind the scenes from Science Magazine goes into how they captured such an exceptional shot.
Read MoreResearchers at EPFL recently found that the RNA-binding protein PUM2 contributes to the accumulation of defective mitochondria, a key feature of the aging process. Targeting this protein in old animals protects against age-related mitochondrial dysfunction. What can this mean for humans though?
Read MoreResearchers in Maryland recently conducted a test examining 3,600 different samples of bacteria from 1,165 healthy individuals age 20-90. They found that bacteria actually differs vastly between various age groups. They think this “microbiome aging clock” could be used as a baseline to test how fast or slow a person’s gut is aging and how different diets might have an effect on longevity.
Read MoreIntestinal worms have long caused suffering in humans, but has our bias against a handful of harmful helminths led us to slaughter billions of helpful ones? Is our quest as humans to eradicate parasitic worms being accomplished to our detriment? And if we could treat or even prevent many of our modern inflammatory diseases with harmless intestinal worms, why don’t we?
Read MoreThere are 3D bioprinters but no 3D printed usable organs. Why is that? Microvascularization is a key rate limiter preventing humans needing an organ transplant from having it made available to them. In other words, blood needs to get to the 3D printed tissue in order for the tissue to remain alive. Thankfully, a start-up we have proudly supported from inception is developing the necessary tools to solve the microvascularization challenge so that we can have functioning 3D printed organs.
Read MoreAn impressive team at Stanford lead by Vittorio Sebastiano, Jay Sarkar, and Marco Quarta has found a way to turn adult cells into younger cells. That way, the cells don’t forget their assigned tasks since they maintain their cell type, but have the added advantage of having restored youthful performance.
Read MoreWhat we know as “essential vitamins and minerals” are compounds whose absence has been observed to be immensely detrimental or even fatal to humans. Think of death by scurvy (vitamin C deficiency) or pellagra (niacin deficiency). But an important question to ask for each essential vitamin and mineral is: “over what timeframe do detrimental effects of deficiency manifest themselves?”
Read MoreThe epigenetic remodeling accomplished by this protocol appears promising, and may help us to rejuvenate older humans.
Read MoreHere is an interesting fact for the dinner table… many studies have correlated longevity with genes and you may find out just how likely you are to surpass the 100 year mark. Did you know that individuals who have centenarian parents have been found to be less likely to have the age-related diseases that are common among older adults?
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