The latest on Methuselah, health span research, and regenerative medicine
Scientists have long suspected that the anti-malarial drug chloroquine may be helpful in treating senescence, the gradual, age-related deterioration of function in living organisms. The problem is that research has found the drug comes with some nasty side-effects, including liver damage, an increased risk of cardiac arrythmia, and gastrointestinal issues.
Read MoreAmericans want to live longer, but are split on whether government should make public health a priority.
Read MoreControlled cellular reprogramming is getting long-overdue attention as a powerful strategy to help fight the effects of aging. The interest is encouraging because it can help us reach the day when we restore the body’s ability to heal itself.
Read MoreThrilled to announce the opening of Phase 2 of the Deep Space Food Challenge! Phase 1 focused on teams from US, Canada, and globally coming together to design innovative concepts of food production systems for future deep space travel. Phase 2 will bring these ideas to life.
Read MoreWe are excited to announce that Methuselah Foundation invested in X-Therma Inc. - a biotechnology company developing breakthroughs for regenerative medicine and organ preservation - who closed an oversubscribed $13M Series A funding round.
Read MoreMethuselah Foundation contributed $1 million to the Albert Einstein College of Medicine to fund its development of engineered replacement brain structures.
Read MorePeople typically don’t associate cryptocurrency with scientific exploration. That’s why the Dogelon Mars ($ELON) community’s recent investment is so historic. The community has donated funds to send prize-winning vascular tissue science to the International Space Station (ISS), where experiments can continue beyond Earth’s gravity. This is a vital first step towards humanity’s dreams of space travel.
Read MoreNew research from Leucadia Therapeutics scientists offers strong evidence that aging by the
cribiform plate (CP) – the portion of the ethmoid bone that forms the roof of the nasal cavity –
plays a critical role in the development of Alzheimer’s disease.
Read MoreNASA and Methuselah Foundation Vascular Tissue Challenge winners from Wake Forest University & Wake Forest Institute for Regenerative Medicine make history by bioengineering and sustaining live human tissue in a laboratory.
Read MoreMethuselah Foundation now controls 43% of the world’s Dogelon Mars ($ELON) cryptocurrency and today announced in a press release that to maximize the $ELON’s long-term value, the non-profit will steward the holdings for at least a year. Any future sales would be done to preserve the cryptocurrency’s value while advancing the Foundation’s mission.
Read MoreWe often hear talk of slowing down our epigenetic, (or aging) clock… but what exactly does that entail? And how can we go about executing this feat? A paper published in 2017 by Sanford Burnham Prebys Medical Discovery Institute (SBP), lays a foundation to “understand the epigenetic contribution to healthy aging and longevity and the molecular basis of the DNA methylation clock.”
Read MoreOur PubMed screening during February 2020 had several especially noteworthy papers to choose from to highlight in our blog. Ultimately however, we decided to focus on this report of a remarkable 36% extension of average female mouse lifespan when given an ovarian transplant in middle-age. These results suggest that, at least in females, ovarian function may affect healthspan and lifespan to a greater extent than is usually appreciated at the present time.
Read MoreThis past week the MIT Technology Review published their 10 Breakthrough Technologies for 2020, and we were excited to see a company we’ve invested in, Oisín Biotechnologies, make the list as one of the “Key Players” in the anti-aging space. Their groundbreaking research and technology is “demonstrating that the solution to mitigating the effects of age-related diseases is to address the damage created by the aging process itself”.
Read MoreWith confirmed cases of COVID-19 in the US, Europe and abroad, a growing number of people are rightly concerned what the odds of them contracting the virus is, how it can be avoided, and how they can prepare for a potential lockdown or quarantine in their area. The below page, from cdc.gov, contains concise and updated information including: the global situation summary, what you need to know, how you can protect your home, and even information for specific audiences such as medical professionals, teachers, and those who travel frequently.
Read MoreA study published in January by researchers in Greece recently focused on the importance of muscle mass in those 45 years of age and older, with no pre-existing heart conditions. Participants in the study were tested and then reassessed 10 years later.
Read MoreAccording to the World Health Organization, more people are now dying from being overweight than underweight. And while obesity has long been known to cause premature death, researchers at Concordia University are now arguing that obesity directly accelerates the mechanisms of aging. The researchers write that obesity influences a number of alterations associated with aging. Hopefully this research will help people better understand how obesity works and stimulate ideas on how to treat it.
Read MoreZombies; Senescent cells resisting death, building up, and wreaking havoc on the aging body. In October we published an interview with our friends at Oisín Bio who are working on removal of these zombie cells without collateral damage. Now at Kings College London, thanks to a £125,000 research grant from Heart Research UK, Senolytic drugs and their practical application will be focused on.
Read MoreOrgans are in high demand. Because of this, biomanufactured organs are viewed by many as the next frontier of scientific research and development. Our friends Jordan Miller, Bagrat Grigoryan, and their team at Volumetric Bio are working to make that a reality now. This article discusses where their research is at now and the practical benefits of what they’re doing.
Read MoreSome 60%-90% of drugs that are successful in rodents… fail in humans. However, researchers at Harvard University and Tel Aviv University have developed a new model that might address this problem: mini human organs on a chip. These separate “organ chips” can be connected to create a “mini human on a chip”, to test the effects of different treatments and medications on multiple organs and systems.
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