The latest on Methuselah, health span research, and regenerative medicine
Scientists have recently discovered a “master control gene” found in salamanders and worms called Early Growth Response that is also present in humans. What could this mean for us? This article explains some of the ins and outs of cell regeneration and how it might not be the presence of certain genes but rather, how they’re wired together that makes this level of cell regeneration possible.
Read MoreSince these “biomarkers” shorten as we age, many companies have begun to offer home tests to potentially show the users “true” biological age, how healthy they are, and their susceptibility to various diseases. But are these tests ready for the public? And is it worth your money to try one?
Read MoreIn the last 50 years the average life expectancy has been extended from 65 to 85, giving us an extra third of our life. Can we enjoy this substantial new chapter of life if we’re slowly being shackled by the bonds of aging? This article by the New Yorker discusses this intriguing topic!
Read MoreOne of our partners, Leucadia Therapeutics, is pleased to announce that Project Cribrose is now live! They are recruiting participants for a 2000 person study, including healthy people from 20-90 years old, those with Alzheimer’s disease, Frontotemporal dementia, or Down Syndrome and people over 50 with mild cognitive impairment.
Read MoreOn May 3 2019 Volumetric Bio made history, and made the cover of Science Magazine with their groundbreaking technology. But how does one go about photographing something smaller than a penny in sharp detail? This behind the scenes from Science Magazine goes into how they captured such an exceptional shot.
Read MoreResearchers at EPFL recently found that the RNA-binding protein PUM2 contributes to the accumulation of defective mitochondria, a key feature of the aging process. Targeting this protein in old animals protects against age-related mitochondrial dysfunction. What can this mean for humans though?
Read MoreResearchers in Maryland recently conducted a test examining 3,600 different samples of bacteria from 1,165 healthy individuals age 20-90. They found that bacteria actually differs vastly between various age groups. They think this “microbiome aging clock” could be used as a baseline to test how fast or slow a person’s gut is aging and how different diets might have an effect on longevity.
Read MoreIntestinal worms have long caused suffering in humans, but has our bias against a handful of harmful helminths led us to slaughter billions of helpful ones? Is our quest as humans to eradicate parasitic worms being accomplished to our detriment? And if we could treat or even prevent many of our modern inflammatory diseases with harmless intestinal worms, why don’t we?
Read MoreLight exposure on the retina of the eye plays a critical role in entraining the circadian rhythm—the daily oscillation of tissue function, including the secretion of different hormones at different times.
Read MoreThere are 3D bioprinters but no 3D printed usable organs. Why is that? Microvascularization is a key rate limiter preventing humans needing an organ transplant from having it made available to them. In other words, blood needs to get to the 3D printed tissue in order for the tissue to remain alive. Thankfully, a start-up we have proudly supported from inception is developing the necessary tools to solve the microvascularization challenge so that we can have functioning 3D printed organs.
Read MoreAn impressive team at Stanford lead by Vittorio Sebastiano, Jay Sarkar, and Marco Quarta has found a way to turn adult cells into younger cells. That way, the cells don’t forget their assigned tasks since they maintain their cell type, but have the added advantage of having restored youthful performance.
Read MoreOn a recent trip to California, my goal was to document an aircraft’s actual interior cabin altitude, versus the altitude of that aircraft’s distance above the ground. Finding this altitude would tell me how much oxygen would be in the cabin, where lower altitudes would mean more available oxygen.
Read MoreWe modestly present a journey into our personal experience with "near field environmental factors" and health. This series will be the first entry in what we hope will become a shared resource that helps us all get better and better. Welcome to N of One!
Read MoreThe elderly have wisdom of great value to all, but few listen. Their story is worth being heard. If things don’t change, we will all share their experience. This first-person narrative is the result of years of interviews and the extensive experience of a Registered Nurse specializing in Geriatrics. We invite you to live a day in the live of a 90 year old.
Read MoreWhat we know as “essential vitamins and minerals” are compounds whose absence has been observed to be immensely detrimental or even fatal to humans. Think of death by scurvy (vitamin C deficiency) or pellagra (niacin deficiency). But an important question to ask for each essential vitamin and mineral is: “over what timeframe do detrimental effects of deficiency manifest themselves?”
Read MoreWhat defines an average 90-year-old scientifically?
What defines a 50-year-old?
How could we make 90 the new 50 by 2030?
The epigenetic remodeling accomplished by this protocol appears promising, and may help us to rejuvenate older humans.
Read MoreHere is an interesting fact for the dinner table… many studies have correlated longevity with genes and you may find out just how likely you are to surpass the 100 year mark. Did you know that individuals who have centenarian parents have been found to be less likely to have the age-related diseases that are common among older adults?
Read MoreWe all want a healthcare system that is more productive and efficient in finding innovative solutions to illnesses and diseases of aging. That is why it is important to look at the factors that need disruption in our journey to creating an inclusive and sustainable healthcare system.
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