The latest on Methuselah, health span research, and regenerative medicine
Many people suffering from chronic illnesses also report that they experience ‘brain fog’ or ‘sluggishness’. A recent study done at the University of Birmingham has attributed this sluggishness, (at least in part), to inflammation. Getting a better understanding of the relationships between inflammation and brain function will help us investigate other ways to treat some of these conditions in patients with chronic illnesses.
Read MoreWe had had the pleasure of attending the conference titled “Master Investor: Investing in the Age of Longevity” that took place in London, England.
Read MoreThis article introduces Reason, an astrophysicist whose passion is longevity, and focuses on Repair Biotechnologies – a company supported by the Methuselah Foundation that is looking to regenerate the thymus and reverse atherosclerosis.
Read MoreThe carotid body is a small organ that plays a role in controlling the breathing rate. In this paper, Di Giulio describes a part of the carotid body that becomes infiltrated with lymphocytes and fibrosis during aging. Much is still unknown about this organ and the effects that it’s aging has on us. As such, we think it is important to monitor scientific literature for data that tells us something we didn’t know, or that contradicts our current understanding of degenerative aging and how we might bring it under complete medical control.
Read MoreIt can be said that cancer has been cured dozens of times over in mice. Oftentimes though, the results obtained in the lab aren’t translatable to humans with the same conditions. This uncertainty often leads to misleading results, frustration, and a waste of resources. With this in mind, the EPA has recently announced that they will stop conducting or funding studies on mammals by 2035. Read More >
Read MoreWe need blood, it delivers nutrients and removes waste. However, there is considerable evidence that during human aging, the network of the smallest blood vessels, microvasculature, atrophy with age. The research group in this paper reported that topical application vitamin C to the skin caused significant regression of senile purpura. For the sake of our mission to Renew the Rivers, we hope to see more research on the aging human microvasculature and what we can do about it.
Read MoreNicotinamide adenine dinucleotide (NAD) has become increasingly popular over the past several years. It’s a metabolite that’s very important in DNA repair and energy production. For whatever reason, it’s concentration is known to decline during human aging by as much as 90%. We hope that NAD restoration in older people can restore biological function in multiple tissues, and the results of this paper are consistent with that hope.
Read MoreFor ages, dogs have been known to bring humans joy, help comfort those with anxiety & depression, reduce stress, the list goes on. But aside from the mental and emotional benefits, what effects can these animals have on our physical well being? A recent paper reviewing 10 different studies, spanning decades, and including thousands of participants showed a strong correlation between dog ownership and a lower risk of death over the long term.
Read MoreIf you have been thinking about attending a longevity conference, feel free to join some of our supported companies at the Longevity World Forum taking place on November 13-15, in Valencia, Spain.
Read MoreWe have started a series of articles that will be published on medium.com. The first article provides a brief history of the Methuselah Foundation and highlights Oisín Biotechnologies – a company we provided founding capital for and continued incubation services and support. With “bio-techie” Matthew Scholz as CEO, Oisín Biotechnologies is tackling aging by selectively killing senescent cells with a targeted DNA approach.
Read MoreScience is barreling toward the cure or prevention of countless diseases. Who knows how many diseases that currently run rampant will be put to rest within the next few years. In the meantime however, those living with chronic illnesses face difficult battles every day. This article, written by a professor of psychology, goes over some practical ways that people suffering from chronic illnesses can improve their outlook in the meantime.
Read MoreAutophagy- The clearing out of old, senescent cells to make room for newer, younger cells. The research group in this paper found that markers of autophagy declined during aging in rats. Could the age-related decline in autophagy be partly to blame for the increased cellular senescence and accumulation of lipofuscin with age?
Read MoreDespite the vast population Alzheimer’s disease affects each year, no new drugs have been approved by the FDA in 16 years. The lack of success in AD drug development has infused scepticism in the field. This recent scientific publication shows the latest developments in the AD drug pipeline as of 2019.
Read MoreIn late 2018, a professor in Sweden conducted a study on the psychological and behavioral aspects of mobile phone use. Her study compiled data from 290 papers and lists some of her findings. Considering mental health is something essential for us to lead happy and healthy lives, and almost all of us use these devices daily, this paper is a good reminder for us all.
Read MoreThe Methuselah Foundation is pleased to be a sponsor of a unique and interesting conference, Targeting Metabesity 2019, at the Carnegie Institution for Science in Washington, DC, from October 15-16, 2019.
Read MoreBiomanufactured organs are the next frontier of scientific research and development. But creating vascularized tissue is a challenging endeavor, however a technique called SWIFT may get us one step closer to overcoming the hurdle of vascularization. They hope to continually improve upon this method with the goal of engineering fully functional, 3D printed human organs. Read what they learned below!
Read MoreIn a recent trial conducted in California, researchers investigated the effects that a recombinant human growth hormone had on the immune systems of 9 healthy men in their 50’s and 60’s. Over the course of one year, on average the trial members shed 2.5 years off of their ‘biological age’. It’s hoped that this newly acquired information regarding the effects these three drugs have on the body could be beneficial for people with under active immune systems, the elderly, and research into infectious diseases, cancer, and aging in general.
Read MoreWhen you hear the phrase, “Making 90 The New 50 By 2030”, does your mind go to the future? Thinking about the deadline? The work left to do? Or do you think about what’s already been accomplished? The progress already made? Because despite the work left to do, science has already come a long way towards reaching the goal. A study from 2018 conducted by Yale and USC Professors shows that in American males 60 might already be the new 50.
Read MoreIf you found a treatment that could to extend your life by up to 30% and increase your resistance to diseases and inflammation, what would you pay for it? What if it was free? That sounds like a no-brainer right? In 1980 one scientist stumbled upon such a treatment while conducting a study on high cholesterol, heart rate, and blood pressure involving rabbits.
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